@import"https://fonts.googleapis.com/css2?family=Inter:wght@300;400;500;600;700;800;900&family=JetBrains+Mono:wght@400;500;600&display=swap";:root{--bg-primary: #f8fafc;--bg-secondary: #ffffff;--bg-tertiary: #f1f5f9;--bg-card: rgba(255, 255, 255, .85);--bg-glass: rgba(255, 255, 255, .6);--bg-glass-hover: rgba(255, 255, 255, .85);--accent-blue: #2563eb;--accent-blue-glow: rgba(37, 99, 235, .2);--accent-purple: #7c3aed;--accent-purple-glow: rgba(124, 58, 237, .2);--accent-cyan: #0891b2;--accent-cyan-glow: rgba(8, 145, 178, .15);--status-green: #059669;--status-green-glow: rgba(5, 150, 105, .15);--status-green-bg: rgba(5, 150, 105, .08);--status-red: #dc2626;--status-red-glow: rgba(220, 38, 38, .15);--status-red-bg: rgba(220, 38, 38, .06);--status-amber: #d97706;--status-amber-glow: rgba(217, 119, 6, .15);--status-amber-bg: rgba(217, 119, 6, .06);--text-primary: #0f172a;--text-secondary: #475569;--text-muted: #64748b;--text-dim: #94a3b8;--border-subtle: rgba(0, 0, 0, .06);--border-medium: rgba(0, 0, 0, .1);--border-accent: rgba(37, 99, 235, .25);--space-xs: 4px;--space-sm: 8px;--space-md: 16px;--space-lg: 24px;--space-xl: 32px;--space-2xl: 48px;--space-3xl: 64px;--radius-sm: 6px;--radius-md: 10px;--radius-lg: 16px;--radius-xl: 20px;--radius-full: 9999px;--font-sans: "Inter", -apple-system, BlinkMacSystemFont, "Segoe UI", sans-serif;--font-mono: "JetBrains Mono", "Fira Code", monospace;--shadow-sm: 0 1px 3px rgba(0, 0, 0, .06), 0 1px 2px rgba(0, 0, 0, .04);--shadow-md: 0 4px 16px rgba(0, 0, 0, .08), 0 2px 4px rgba(0, 0, 0, .04);--shadow-lg: 0 12px 40px rgba(0, 0, 0, .1), 0 4px 12px rgba(0, 0, 0, .05);--shadow-glow-blue: 0 4px 24px rgba(37, 99, 235, .12);--shadow-glow-green: 0 4px 24px rgba(5, 150, 105, .12);--shadow-glow-red: 0 4px 24px rgba(220, 38, 38, .12);--shadow-glow-amber: 0 4px 24px rgba(217, 119, 6, .12);--transition-fast: .15s cubic-bezier(.4, 0, .2, 1);--transition-base: .25s cubic-bezier(.4, 0, .2, 1);--transition-slow: .4s cubic-bezier(.4, 0, .2, 1);--transition-spring: .5s cubic-bezier(.34, 1.56, .64, 1)}[data-theme=dark]{--bg-primary: #0a0e17;--bg-secondary: #111827;--bg-tertiary: #1a2035;--bg-card: rgba(17, 24, 39, .7);--bg-glass: rgba(255, 255, 255, .03);--bg-glass-hover: rgba(255, 255, 255, .06);--accent-blue: #3b82f6;--accent-blue-glow: rgba(59, 130, 246, .3);--accent-purple: #8b5cf6;--accent-purple-glow: rgba(139, 92, 246, .3);--accent-cyan: #06b6d4;--accent-cyan-glow: rgba(6, 182, 212, .2);--status-green: #10b981;--status-green-glow: rgba(16, 185, 129, .25);--status-green-bg: rgba(16, 185, 129, .1);--status-red: #ef4444;--status-red-glow: rgba(239, 68, 68, .25);--status-red-bg: rgba(239, 68, 68, .1);--status-amber: #f59e0b;--status-amber-glow: rgba(245, 158, 11, .25);--status-amber-bg: rgba(245, 158, 11, .1);--text-primary: #f1f5f9;--text-secondary: #94a3b8;--text-muted: #64748b;--text-dim: #475569;--border-subtle: rgba(255, 255, 255, .06);--border-medium: rgba(255, 255, 255, .1);--border-accent: rgba(59, 130, 246, .3);--shadow-sm: 0 1px 2px rgba(0, 0, 0, .3);--shadow-md: 0 4px 12px rgba(0, 0, 0, .4);--shadow-lg: 0 8px 32px rgba(0, 0, 0, .5);--shadow-glow-blue: 0 0 20px rgba(59, 130, 246, .15);--shadow-glow-green: 0 0 30px rgba(16, 185, 129, .2);--shadow-glow-red: 0 0 30px rgba(239, 68, 68, .2);--shadow-glow-amber: 0 0 30px rgba(245, 158, 11, .2)}*,*:before,*:after{margin:0;padding:0;box-sizing:border-box}html{font-size:16px;-webkit-font-smoothing:antialiased;-moz-osx-font-smoothing:grayscale}body{font-family:var(--font-sans);background:var(--bg-primary);color:var(--text-primary);line-height:1.6;min-height:100vh;overflow-x:hidden;transition:background var(--transition-base),color var(--transition-base)}body:before{content:"";position:fixed;inset:0;background:radial-gradient(ellipse at 15% 0%,rgba(37,99,235,.05) 0%,transparent 50%),radial-gradient(ellipse at 85% 100%,rgba(124,58,237,.04) 0%,transparent 50%),radial-gradient(ellipse at 50% 50%,rgba(8,145,178,.03) 0%,transparent 60%);pointer-events:none;z-index:0}[data-theme=dark] body:before{background:radial-gradient(ellipse at 20% 0%,rgba(59,130,246,.08) 0%,transparent 50%),radial-gradient(ellipse at 80% 100%,rgba(139,92,246,.06) 0%,transparent 50%),radial-gradient(ellipse at 50% 50%,rgba(6,182,212,.04) 0%,transparent 60%)}#root{position:relative;z-index:1;min-height:100vh;display:flex;flex-direction:column}a{color:var(--accent-blue);text-decoration:none;transition:color var(--transition-fast)}a:hover{color:var(--accent-cyan)}::-webkit-scrollbar{width:6px;height:6px}::-webkit-scrollbar-track{background:transparent}::-webkit-scrollbar-thumb{background:var(--text-dim);border-radius:var(--radius-full)}::-webkit-scrollbar-thumb:hover{background:var(--text-muted)}.app-header{position:sticky;top:0;z-index:100;background:#ffffffd1;backdrop-filter:blur(20px) saturate(180%);-webkit-backdrop-filter:blur(20px) saturate(180%);border-bottom:1px solid var(--border-subtle);padding:var(--space-md) var(--space-xl);display:flex;align-items:center;justify-content:space-between;gap:var(--space-lg);transition:background var(--transition-base)}[data-theme=dark] .app-header{background:#0a0e17d9}.app-logo{display:flex;align-items:center;gap:var(--space-md);cursor:pointer}.app-logo-icon{width:44px;height:44px;border-radius:var(--radius-md);background:linear-gradient(135deg,var(--accent-blue),var(--accent-purple));display:flex;align-items:center;justify-content:center;font-size:22px;font-weight:800;color:#fff;box-shadow:var(--shadow-glow-blue)}.app-logo-text{font-size:24px;font-weight:700;background:linear-gradient(135deg,var(--text-primary) 0%,var(--accent-blue) 100%);-webkit-background-clip:text;-webkit-text-fill-color:transparent;background-clip:text}.app-logo-badge{font-size:10px;font-weight:600;text-transform:uppercase;letter-spacing:.08em;padding:2px 8px;border-radius:var(--radius-full);background:var(--status-green-bg);color:var(--status-green);border:1px solid rgba(5,150,105,.2)}.app-logo-badge.live{background:#2563eb14;color:var(--accent-blue);border:1px solid rgba(37,99,235,.2)}.app-nav{display:flex;gap:var(--space-sm);position:absolute;left:50%;transform:translate(-50%)}.app-nav-btn{padding:var(--space-sm) var(--space-md);border-radius:var(--radius-md);border:1px solid transparent;background:transparent;color:var(--text-secondary);font-family:var(--font-sans);font-size:13px;font-weight:500;cursor:pointer;transition:all var(--transition-fast);display:flex;align-items:center;gap:var(--space-sm)}.app-nav-btn:hover{background:var(--bg-glass-hover);color:var(--text-primary);border-color:var(--border-subtle)}.app-nav-btn.active{background:#2563eb14;color:var(--accent-blue);border-color:#2563eb26}[data-theme=dark] .app-nav-btn.active{background:#3b82f61a;border-color:#3b82f633}.app-right-group{display:flex;align-items:center;gap:var(--space-md)}.app-status{display:flex;align-items:center;gap:var(--space-sm);font-size:12px;color:var(--text-muted)}.app-status-dot{width:8px;height:8px;border-radius:50%;background:var(--status-green);box-shadow:0 0 8px var(--status-green-glow);animation:pulse-subtle 2s ease-in-out infinite}@keyframes pulse-subtle{0%,to{opacity:1}50%{opacity:.5}}.theme-toggle{width:38px;height:38px;border-radius:var(--radius-md);border:1px solid var(--border-medium);background:var(--bg-glass);color:var(--text-secondary);font-size:18px;cursor:pointer;display:flex;align-items:center;justify-content:center;transition:all var(--transition-fast)}.theme-toggle:hover{background:var(--bg-glass-hover);color:var(--text-primary);border-color:var(--accent-blue);box-shadow:var(--shadow-glow-blue);transform:rotate(15deg)}.app-main{flex:1;padding:var(--space-xl);max-width:1600px;margin:0 auto;width:100%}.glass-card{background:var(--bg-card);backdrop-filter:blur(12px) saturate(150%);-webkit-backdrop-filter:blur(12px) saturate(150%);border:1px solid var(--border-subtle);border-radius:var(--radius-lg);padding:var(--space-lg);box-shadow:var(--shadow-sm);transition:all var(--transition-base)}.glass-card:hover{border-color:var(--border-medium);box-shadow:var(--shadow-md)}.glass-card-glow-green{border-color:#0596694d;box-shadow:var(--shadow-glow-green)}.glass-card-glow-red{border-color:#dc26264d;box-shadow:var(--shadow-glow-red)}.glass-card-glow-amber{border-color:#d977064d;box-shadow:var(--shadow-glow-amber)}.btn{display:inline-flex;align-items:center;justify-content:center;gap:var(--space-sm);padding:10px 20px;border-radius:var(--radius-md);border:1px solid transparent;font-family:var(--font-sans);font-size:14px;font-weight:600;cursor:pointer;transition:all var(--transition-base);white-space:nowrap}.btn-primary{background:linear-gradient(135deg,var(--accent-blue),var(--accent-purple));color:#fff;box-shadow:0 2px 12px #2563eb40}.btn-primary:hover{box-shadow:0 4px 20px #2563eb66;transform:translateY(-1px)}.btn-primary:active{transform:translateY(0)}.btn-secondary{background:var(--bg-glass);color:var(--text-primary);border-color:var(--border-medium)}.btn-secondary:hover{background:var(--bg-glass-hover);border-color:var(--accent-blue)}.btn-ghost{background:transparent;color:var(--text-secondary)}.btn-ghost:hover{background:var(--bg-glass);color:var(--text-primary)}.btn-sm{padding:6px 14px;font-size:12px}.btn-lg{padding:14px 28px;font-size:16px}.btn:disabled{opacity:.5;cursor:not-allowed;transform:none!important}.section-header{margin-bottom:var(--space-lg)}.section-title{font-size:24px;font-weight:700;margin-bottom:var(--space-xs);background:linear-gradient(135deg,var(--text-primary),var(--accent-blue));-webkit-background-clip:text;-webkit-text-fill-color:transparent;background-clip:text}.section-subtitle{font-size:14px;color:var(--text-muted)}.badge{display:inline-flex;align-items:center;gap:4px;padding:3px 10px;border-radius:var(--radius-full);font-size:11px;font-weight:600;text-transform:uppercase;letter-spacing:.05em}.badge-green{background:var(--status-green-bg);color:var(--status-green);border:1px solid rgba(5,150,105,.2)}.badge-red{background:var(--status-red-bg);color:var(--status-red);border:1px solid rgba(220,38,38,.2)}.badge-amber{background:var(--status-amber-bg);color:var(--status-amber);border:1px solid rgba(217,119,6,.2)}.badge-blue{background:#2563eb14;color:var(--accent-blue);border:1px solid rgba(37,99,235,.15)}[data-theme=dark] .badge-green{border-color:#10b98133}[data-theme=dark] .badge-red{border-color:#ef444433}[data-theme=dark] .badge-amber{border-color:#f59e0b33}[data-theme=dark] .badge-blue{border-color:#3b82f633}.progress-bar-container{width:100%;height:6px;background:var(--bg-tertiary);border-radius:var(--radius-full);overflow:hidden;position:relative}.progress-bar-fill{height:100%;border-radius:var(--radius-full);background:linear-gradient(90deg,var(--accent-blue),var(--accent-purple));transition:width .6s cubic-bezier(.4,0,.2,1);position:relative}.progress-bar-fill:after{content:"";position:absolute;inset:0;background:linear-gradient(90deg,transparent,rgba(255,255,255,.3),transparent);animation:shimmer 2s ease-in-out infinite}@keyframes shimmer{0%{transform:translate(-100%)}to{transform:translate(100%)}}.split-screen{display:grid;grid-template-columns:420px 1fr;gap:var(--space-lg);height:calc(100vh - 160px);min-height:500px}.split-panel{overflow-y:auto;overflow-x:hidden;padding-right:var(--space-sm)}.patient-record{font-family:var(--font-mono);font-size:12px;line-height:1.7;color:var(--text-secondary);white-space:pre-wrap;word-break:break-word}.patient-record .evidence-highlight{background:#2563eb0f;padding:2px 8px;margin:0 -8px;border-radius:0 var(--radius-sm) var(--radius-sm) 0;color:var(--text-secondary);transition:all .3s ease}.patient-record .evidence-highlight.evidence-highlight-active{background:#2563eb2e;border-left:3px solid var(--accent-blue);color:var(--text-primary);font-weight:500;box-shadow:0 0 16px #2563eb1f;animation:evidence-glow 2s ease-in-out infinite}[data-theme=dark] .patient-record .evidence-highlight{background:#3b82f60f}[data-theme=dark] .patient-record .evidence-highlight.evidence-highlight-active{background:#3b82f640;border-left:3px solid #60a5fa;box-shadow:0 0 20px #3b82f633}@keyframes evidence-glow{0%,to{box-shadow:0 0 16px #2563eb1f}50%{box-shadow:0 0 24px #2563eb40}}@keyframes evidence-glow-dark{0%,to{box-shadow:0 0 16px #3b82f633}50%{box-shadow:0 0 28px #3b82f659}}[data-theme=dark] .patient-record .evidence-highlight.evidence-highlight-active{animation-name:evidence-glow-dark}.patient-record .evidence-highlight.evidence-highlight-pass2{background:#dc262614}.patient-record .evidence-highlight.evidence-highlight-pass2.evidence-highlight-active{background:#dc262633;border-left:3px solid var(--status-red);color:var(--text-primary);font-weight:500;box-shadow:0 0 16px #dc262626;animation:evidence-glow-pass2 2s ease-in-out infinite}[data-theme=dark] .patient-record .evidence-highlight.evidence-highlight-pass2{background:#ef444414}[data-theme=dark] .patient-record .evidence-highlight.evidence-highlight-pass2.evidence-highlight-active{background:#ef444447;border-left:3px solid #f87171;box-shadow:0 0 20px #ef444440;animation-name:evidence-glow-pass2-dark}@keyframes evidence-glow-pass2{0%,to{box-shadow:0 0 16px #dc262626}50%{box-shadow:0 0 24px #dc26264d}}@keyframes evidence-glow-pass2-dark{0%,to{box-shadow:0 0 16px #ef444440}50%{box-shadow:0 0 28px #ef444466}}.patient-record .pass2-separator{display:block;margin:10px -8px;padding:4px 10px;background:#dc26261a;border-left:3px solid var(--status-red);color:var(--status-red);font-size:10px;font-weight:700;letter-spacing:.08em;text-transform:uppercase;border-radius:0 4px 4px 0}[data-theme=dark] .patient-record .pass2-separator{background:#ef44441f;color:#f87171;border-left-color:#f87171}.criterion-hovered{border-color:var(--accent-blue)!important;box-shadow:0 0 8px var(--accent-blue-glow)!important;transform:translate(4px)}.patient-record-header{position:sticky;top:0;z-index:10;background:var(--bg-card);-webkit-backdrop-filter:blur(12px);backdrop-filter:blur(12px);padding:12px 16px;border-bottom:1px solid var(--border-subtle);display:flex;align-items:center;gap:var(--space-md)}.criterion-card{background:var(--bg-glass);border:1px solid var(--border-subtle);border-radius:var(--radius-md);padding:var(--space-md);margin-bottom:var(--space-sm);transition:all var(--transition-base);cursor:default;box-shadow:var(--shadow-sm)}.criterion-card.evaluating{border-color:var(--accent-blue);box-shadow:0 0 12px var(--accent-blue-glow);animation:pulse-border 1.5s ease-in-out infinite}@keyframes pulse-border{0%,to{border-color:var(--accent-blue);box-shadow:0 0 12px var(--accent-blue-glow)}50%{border-color:var(--accent-cyan);box-shadow:0 0 20px var(--accent-cyan-glow)}}.criterion-card.status-met{border-color:#0596694d;background:var(--status-green-bg)}.criterion-card.status-not-met-inclusion,.criterion-card.status-met-exclusion{border-color:#dc26264d;background:var(--status-red-bg)}.criterion-card.status-insufficient{border-color:#d977064d;background:var(--status-amber-bg)}.criterion-header{display:flex;align-items:flex-start;gap:var(--space-sm);margin-bottom:var(--space-sm)}.criterion-icon{width:24px;height:24px;border-radius:var(--radius-sm);display:flex;align-items:center;justify-content:center;font-size:14px;flex-shrink:0;margin-top:1px}.criterion-icon.pending{background:var(--bg-tertiary);color:var(--text-dim);border:1px solid var(--border-subtle)}.criterion-icon.evaluating{background:#2563eb1f;color:var(--accent-blue);animation:spin 1.5s linear infinite}[data-theme=dark] .criterion-icon.evaluating{background:#3b82f633}@keyframes spin{0%{transform:rotate(0)}to{transform:rotate(360deg)}}.criterion-icon.passed{background:var(--status-green-bg);color:var(--status-green)}.criterion-icon.failed{background:var(--status-red-bg);color:var(--status-red)}.criterion-icon.review{background:var(--status-amber-bg);color:var(--status-amber)}.criterion-id{font-family:var(--font-mono);font-size:11px;font-weight:600;color:var(--text-muted);margin-bottom:2px}.criterion-rule{font-size:13px;color:var(--text-primary);line-height:1.5}.criterion-evidence{margin-top:var(--space-sm);padding-top:var(--space-sm);border-top:1px solid var(--border-subtle)}.criterion-evidence-quote{font-family:var(--font-mono);font-size:11px;color:var(--accent-cyan);background:#0891b20d;padding:var(--space-xs) var(--space-sm);border-radius:var(--radius-sm);border-left:2px solid var(--accent-cyan);margin-bottom:var(--space-xs);line-height:1.5}[data-theme=dark] .criterion-evidence-quote{background:#06b6d40d}.criterion-reasoning{font-size:12px;color:var(--text-secondary);margin-top:var(--space-sm);line-height:1.6}.criterion-confidence{display:inline-flex;align-items:center;gap:4px;margin-top:var(--space-xs)}.result-banner{border-radius:var(--radius-xl);padding:var(--space-xl) var(--space-2xl);text-align:center;animation:banner-appear .6s cubic-bezier(.34,1.56,.64,1)}@keyframes banner-appear{0%{opacity:0;transform:scale(.9) translateY(20px)}to{opacity:1;transform:scale(1) translateY(0)}}.result-banner.matched{background:linear-gradient(135deg,#0596691a,#0891b20f);border:1px solid rgba(5,150,105,.25);box-shadow:var(--shadow-glow-green)}.result-banner.excluded{background:linear-gradient(135deg,#dc262614,#d977060d);border:1px solid rgba(220,38,38,.25);box-shadow:var(--shadow-glow-red)}.result-banner.human-review{background:linear-gradient(135deg,#d9770614,#2563eb0d);border:1px solid rgba(217,119,6,.25);box-shadow:var(--shadow-glow-amber)}[data-theme=dark] .result-banner.matched{background:linear-gradient(135deg,#10b98126,#06b6d41a);border-color:#10b9814d}[data-theme=dark] .result-banner.excluded{background:linear-gradient(135deg,#ef444426,#f59e0b1a);border-color:#ef44444d}[data-theme=dark] .result-banner.human-review{background:linear-gradient(135deg,#f59e0b26,#3b82f61a);border-color:#f59e0b4d}.result-banner-icon{font-size:48px;margin-bottom:var(--space-md)}.result-banner-title{font-size:28px;font-weight:800;margin-bottom:var(--space-sm)}.result-banner-subtitle{font-size:15px;color:var(--text-secondary);max-width:600px;margin:0 auto}.patient-card{background:var(--bg-glass);border:1px solid var(--border-subtle);border-radius:var(--radius-lg);padding:var(--space-lg);cursor:pointer;transition:all var(--transition-base);display:flex;align-items:center;gap:var(--space-md);box-shadow:var(--shadow-sm)}.patient-card:hover{border-color:var(--accent-blue);background:var(--bg-glass-hover);transform:translateY(-2px);box-shadow:var(--shadow-glow-blue)}.patient-card.selected{border-color:var(--accent-blue);background:#2563eb0f;box-shadow:var(--shadow-glow-blue)}[data-theme=dark] .patient-card.selected{background:#3b82f614}.patient-card.patient-new-import{animation:importBlink .6s ease-in-out 4;border-color:#10b98180}@keyframes importBlink{0%,to{border-color:#10b98180;box-shadow:0 0 #10b98100;background:var(--bg-glass)}50%{border-color:#10b981cc;box-shadow:0 0 12px 2px #10b98126;background:#10b9810f}}.patient-avatar{width:48px;height:48px;border-radius:var(--radius-md);background:linear-gradient(135deg,var(--accent-blue),var(--accent-purple));display:flex;align-items:center;justify-content:center;font-weight:700;font-size:16px;color:#fff;flex-shrink:0}.patient-info{flex:1;min-width:0}.patient-name{font-size:15px;font-weight:600;margin-bottom:2px}.patient-summary{font-size:12px;color:var(--text-muted);line-height:1.4}.trial-card{background:var(--bg-glass);border:1px solid var(--border-subtle);border-radius:var(--radius-lg);padding:var(--space-lg);cursor:pointer;transition:all var(--transition-base);box-shadow:var(--shadow-sm)}.trial-card:hover{border-color:var(--accent-blue);background:var(--bg-glass-hover);box-shadow:var(--shadow-glow-blue)}.trial-card-phase{display:inline-block;padding:2px 8px;border-radius:var(--radius-full);background:#7c3aed1a;color:var(--accent-purple);font-size:11px;font-weight:600;margin-bottom:var(--space-sm)}[data-theme=dark] .trial-card-phase{background:#8b5cf626}.trial-card-title{font-size:15px;font-weight:600;margin-bottom:var(--space-sm);line-height:1.4}.trial-card-meta{display:flex;gap:var(--space-md);font-size:12px;color:var(--text-muted)}.text-area{width:100%;min-height:200px;background:var(--bg-secondary);border:1px solid var(--border-medium);border-radius:var(--radius-md);padding:var(--space-md);color:var(--text-primary);font-family:var(--font-mono);font-size:13px;line-height:1.6;resize:vertical;transition:border-color var(--transition-fast)}[data-theme=dark] .text-area{background:var(--bg-tertiary)}.text-area:focus{outline:none;border-color:var(--accent-blue);box-shadow:0 0 0 3px var(--accent-blue-glow)}.text-area::placeholder{color:var(--text-dim)}.input{width:100%;height:42px;background:var(--bg-secondary);border:1px solid 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